Glucocorticoids in Leprosy Reversal reaction
نویسندگان
چکیده
منابع مشابه
Successful plasma exchange in type 1 leprosy reversal reaction.
A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine. After four months he developed a reversal reaction and the diagnosis was modified to borderline tuberculoid leprosy. The dose of clofazimine was raised and prednisolone added to the regimen without any symptomatic response. His condition improved dramatically after f...
متن کاملUnilateral oedema of reversal reaction (RR) in borderline leprosy.
UNILATERAL OEDEMA OF REVERSAL REACTION (RR) IN BORDERLINE LEPROSY Sir, Oedema is a well recognized feature in leprosy, especially during reactions. But oedema in only one extremity or on one side of the fa ce is a rare, though documented occurrence . In 1 983 while I was a volunteer doctor at the Nonsombun Leprosy Hospital in Khon Kaen, Thai land, 1 had 2 patients in whom 1 observed this intere...
متن کاملLate reversal reaction after 10 years of adequately treated leprosy.
Differentiation between a relapse or late reversal reaction following completion of regular drug therapy in patients with leprosy is often difficult, though it has definite therapeutic implications. The present case documents a late reversal reaction occurring an unusually long time after the completion of multi-drug therapy.
متن کاملDiagnosis and treatment of leprosy type 1 (reversal) reaction.
Leprosy is a chronic granulomatous infection caused by the organism Mycobacterium leprae that primarily affects the skin and peripheral nerves. Leprosy has several distinct clinical presentations ranging from moderate to severe, with the extent of disease generally depending on the host's immune response to the infection. Treatment typically involves antimicrobials (eg, clofazimine, dapsone, ri...
متن کاملIncreased levels of nitric oxide metabolites in urine from leprosy patients in reversal reaction.
We measured the metabolites of NO [nitrite (NO2-) and nitrate (NO3-)] in urine from Ethiopian patients suffering from leprosy. The urinary level of NO2-/NO3- in a group of healthy Ethiopians was 1020 +/- 471 microM (n = 22). Leprosy patients in reversal reaction had significantly higher levels of NO2-/NO3- (1817 +/- 492 microM, p < 0.001, n = 12) than both the control group and leprosy patients...
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ژورنال
عنوان ژورنال: Serbian Journal of Dermatology and Venereology
سال: 2019
ISSN: 2406-0631,1821-0902
DOI: 10.2478/sjdv-2019-0011